Susceptibility Testing for Mycobacteria

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Evaluation of Etest for susceptibility testing of rapidly growing mycobacteria.

MICs of amikacin, cefoxitin, ciprofloxacin, clarithromycin, doxycycline, and imipenem were determined by Etest for 100 clinical strains of rapidly growing mycobacteria and compared with MICs determined by a reference agar dilution method. Etest MICs were also determined by an alternative inoculum application (agar overlay) method and compared with MICs determined by the inoculum application met...

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Rapid susceptibility testing for nontuberculosis mycobacteria using flow cytometry.

We demonstrated previously that susceptibility testing of Mycobacterium tuberculosis could be accomplished within 24 h after the organisms were incubated with antituberculosis agents by using fluorescein diacetate (FDA) staining and flow cytometry. Continued studies have now shown that assay suspensions containing M. avium, M. fortuitum, M. gordonae, or M. marinum incubated with various concent...

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Antimicrobial susceptibility testing of rapidly growing mycobacteria isolated in Japan

BACKGROUND Difficult-to-treat infections caused by rapidly growing mycobacteria (RGM) are increasingly observed in clinical settings. However, studies on antimicrobial susceptibilities and effective treatments against RGM in Japan are limited. METHODS We conducted susceptibility testing of potential antimicrobial agents, including tigecycline and tebipenem, against RGM. Clinical RGM isolates ...

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Drug susceptibility testing of rapidly growing mycobacteria in extrapulmonary tuberculosis.

There has been an increasing awareness of the rapidly growing mycobacteria (RGM), of which numerous species and phylogenetic groups are clearly established human pathogens. It is important to appropriately distinguish RGM from other mycobacteria, as first-line antituberculous drugs are ineffective for their treatment. Variability in susceptibility of RGM is seen in relation to species, differen...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2000

ISSN: 1058-4838,1537-6591

DOI: 10.1086/317441